Tommaso Ristori,
O. M. J. A. (Oscar) Stassen,
C. M. (Cecilia) Sahlgren,
S. (Sandra) Loerakker,
Version 1 of Dataset published 2020 via 4TU.ResearchData
This study extends a previous 1D agent-based model for Notch signaling in arteries to a 2D formulation. This allows investigation of the effects of cell connectivity on the dynamics of arterial Notch signaling and VSMC phenotypes. Notch signaling for VSMCs with 2-6 neighbouring cells was analyzed. Computational results of the 1D and 2D formulations were also compared.